Timothy Eley Selected Research

asunaprevir

6/2018	Population Pharmacokinetic Analysis of Asunaprevir in Subjects with Hepatitis C Virus Infection.
2/2016	A highly sensitive and selective LC-MS/MS method to quantify asunaprevir, an HCV NS3 protease inhibitor, in human plasma in support of pharmacokinetic studies.
2/2016	Daclatasvir + asunaprevir + beclabuvir ± ribavirin for chronic HCV genotype 1-infected treatment-naive patients.
12/2015	Asunaprevir: A Review of Preclinical and Clinical Pharmacokinetics and Drug-Drug Interactions.
3/2015	Multiplexed LC-MS/MS method for the simultaneous quantitation of three novel hepatitis C antivirals, daclatasvir, asunaprevir, and beclabuvir in human plasma.
12/2014	Randomized trial of asunaprevir plus peginterferon alfa and ribavirin for previously untreated genotype 1 or 4 chronic hepatitis C.
6/2014	Daclatasvir plus asunaprevir for chronic HCV genotype 1b infection.
2/2014	Efficacy of an interferon- and ribavirin-free regimen of daclatasvir, asunaprevir, and BMS-791325 in treatment-naive patients with HCV genotype 1 infection.
10/2013	Pharmacokinetics of the NS3 Protease Inhibitor, Asunaprevir (ASV, BMS-650032), in Phase I Studies in Subjects With or Without Chronic Hepatitis C.
4/2013	Dual oral therapy with daclatasvir and asunaprevir for patients with HCV genotype 1b infection and limited treatment options.

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Timothy Eley Research Topics

Disease

17	Infections 06/2018 - 01/2012
11	Chronic Hepatitis C 01/2018 - 01/2012
4	Diarrhea 01/2018 - 04/2012
3	Fibrosis (Cirrhosis) 06/2018 - 02/2014
3	Virus Diseases (Viral Diseases) 01/2018 - 01/2016
3	Hepatitis C 03/2015 - 01/2012
3	Headache (Headaches) 06/2014 - 04/2012
2	Breast Neoplasms (Breast Cancer) 01/2018 - 11/2016
2	Nasopharyngitis 06/2014 - 04/2013
2	Hyperbilirubinemia 10/2013 - 04/2013
1	Body Weight (Weight, Body) 10/2017
1	Fever (Fevers) 06/2014
1	Neonatal Hyperbilirubinemia 10/2013
1	BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia) 06/2009

Drug/Important Bio-Agent (IBA)

12	asunaprevirIBA 06/2018 - 04/2012
11	Ribavirin (Virazole)FDA LinkGeneric 11/2016 - 01/2012
10	Antiviral Agents (Antivirals)IBA 11/2016 - 01/2012
9	daclatasvirIBA 01/2018 - 04/2013
8	Protease Inhibitors (Protease Inhibitor)IBA 02/2016 - 04/2012
7	InterferonsIBA 02/2016 - 04/2012
5	8- cyclohexyl- N- ((dimethylamino)sulfonyl)- 1,1a,2,12b- tetrahydro- 11- methoxy- 1a- ((3- methyl- 3,8- diazabicyclo(3.2.1)oct- 8- yl)carbonyl)cycloprop(d)indolo(2,1- a)(2)benzazepine- 5- carboxamideIBA 02/2016 - 02/2014
4	RNA (Ribonucleic Acid)IBA 03/2014 - 01/2012
3	Peptides (Polypeptides)IBA 03/2018 - 11/2016
3	Member 1 Subfamily B ATP Binding Cassette TransporterIBA 03/2018 - 11/2016
2	Aspartate Aminotransferases (Aspartate Transaminase)IBA 06/2018 - 06/2014
2	AnionsIBA 03/2018 - 11/2016
2	Proteins (Proteins, Gene)FDA Link 01/2018 - 11/2016
2	Alanine Transaminase (SGPT)IBA 10/2017 - 06/2014
2	telaprevirIBA 02/2014 - 01/2014
2	N- (3- amino- 1- (cyclobutylmethyl)- 2,3- dioxopropyl)- 3- (2- ((((1,1- dimethylethyl)amino)carbonyl)amino)- 3,3- dimethyl- 1- oxobutyl)- 6,6- dimethyl- 3- azabicyclo(3.1.0)hexan- 2- carboxamideIBA 02/2014 - 01/2014
1	Flurbiprofen (Froben)FDA LinkGeneric 03/2018
1	Caffeine (No Doz)FDA LinkGeneric 03/2018
1	Digoxin (Digitek)FDA LinkGeneric 03/2018
1	montelukast (Singulair)FDA Link 03/2018
1	Metoprolol (Toprol-XL)FDA LinkGeneric 03/2018
1	Midazolam (Versed)FDA LinkGeneric 03/2018
1	Omeprazole (Prilosec)FDA LinkGeneric 03/2018
1	Pravastatin (Pravachol)FDA LinkGeneric 03/2018
1	Cytochrome P-450 CYP1A2 (CYP1A2)IBA 03/2018
1	Cytochrome P-450 CYP2D6 (CYP2D6)IBA 03/2018
1	Cytochrome P-450 CYP3AIBA 03/2018
1	Cytochrome P-450 CYP2C8IBA 03/2018
1	Cytochrome P-450 CYP2C9IBA 03/2018
1	Cytochrome P-450 CYP2C19IBA 03/2018
1	Rosuvastatin Calcium (Crestor)FDA Link 01/2018
1	Organic Cation Transporter 1IBA 01/2018
1	Amylases FDA Link 01/2018
1	CreatinineIBA 10/2017
1	Cytochrome P-450 Enzyme System (Cytochrome P450)IBA 11/2016
1	Pharmaceutical PreparationsIBA 09/2014
1	InterleukinsIBA 02/2014
1	NucleosidesIBA 02/2014
1	SofosbuvirIBA 01/2014
1	Atazanavir Sulfate (Reyataz)FDA Link 10/2013
1	Transaminases (Aminotransferases)IBA 04/2013
1	Dasatinib (BMS 354825)FDA Link 06/2009
1	Tyrosine Kinase InhibitorsIBA 06/2009

Therapy/Procedure

5	Therapeutics 02/2016 - 01/2012